Contacto
Cómo comprar
Entrega
Guía de compras
Computing Characterizations of Drugs for Ion Channels and Receptors Using Markov Models
Inglés
139 b
Hasta 30 días para devoluciones
Clientes que también han comprado
/
Tapa blanda
45.29
€
/
Tapa blanda
58.09
€
/
Tapa blanda
33.79
€
Flow of ions through voltage gated channels can be represented theoretically using stochastic differential equations where the gating mechanism is represented by a Markov model. The flow through a channel can be manipulated using various drugs, and the effect of a given drug can be reflected by changing the Markov model. These lecture notes provide an accessible introduction to the mathematical methods needed to deal with these models. They emphasize the use of numerical methods and provide sufficient details for the reader to implement the models and thereby study the effect of various drugs. Examples in the text include stochastic calcium release from internal storage systems in cells, as well as stochastic models of the transmembrane potential. Well known Markov models are studied and a systematic approach to including the effect of mutations is presented. Lastly, the book shows how to derive the optimal properties of a theoretical model of a drug for a given mutation defined in terms of a Markov model.
Sobre el libro
Inglés
Regale este libro hoy
Es fácil
1 Añadir al carrito y elegir Entregar como regalo en el checkout 2 Le enviaremos un vale 3 El libro llegará a la dirección del destinatarioTambién puede interesarle
/
Adobe ePub DRM
11.59
€
/
Tapa blanda
20.09
€
/
Tapa blanda
20.29
€
/
Tapa dura
30.79
€
/
Tapa blanda
35.49
€
