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Platelet Concentrates
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Amongst the greatest challenges facing clinical research is the development of bioactive surgical additives regulating in_ammation and increasing healing. Healing is a complex process that involves celluar organization, chemical signals, extracellular matrix and tissue repair. Healing of hard and soft tissue is mediated by a wide range of intra and extracellular events that are regulated by signalling proteins. Understanding the entire process is still incomplete. However, it is known that platelets play a crucial role not only in hemostasis, but also in the wound healing process. With the evolution of platelet concentrate technologies, the trend for local application of growth factors surged, many authors tried to compare the characteristics of the various PRP (Platelet-Rich Plasma) techniques available. Though these products offer interesting therapeutic perspectives, their clinical relevance is largely debated, as the literature on this topic is often confusing and contradictory. The purpose of this book is to have a simplified and detailed knowledge of all the aspects of platelet concentrates.
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