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The Multitasking Molecular Chaperone HSP60
Structure, Function, and Impact on Health and Disease
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The Multitasking Molecular Chaperone HSP60: Structure, Function, and Impact on Health and Disease provides a complete overview of HSP60. It analyzes the molecular structure, localization and functions of HSP60 in normal and pathological cells and tissues in humans. The book then moves on to discuss the role of abnormal HSP60 in disease, considering it across a wide range of skin disorders, heart and blood vessel diseases, respiratory diseases and digestive disorders among others. Genetic chaperonopathies are also covered, and the book moves on to discussion of Hsp60-based therapeutic strategies that can be implemented in the treatment of some diseases.
This book is an invaluable reference for researchers and students in molecular biology, biochemistry, biophysics, biomedicine, pharmacology and related life sciences.
- Discusses therapeutic strategies for diagnosis, patient monitoring, and treatment of disorders in which HSP60 plays a role
- Considers the fundamental biophysics, genetics, and comparative phylogeny of HSP60
- Explores the mechanisms involving HSP60 abnormalities that lead to disease, including carcinogenesis, inflammation, autoimmunity, and neurodegenerative disorders
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