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Tumor Suppressor Genes

Name: Tumor Suppressor Genes
Brand: Humana Press Inc.
SKU: 02644035
Price: 121.69 EUR
Availability: InStock
Author: Wafik S. El-Deiry
ISBN: 9781489939142

Volume 2: Regulation, Function, and Medicinal Applications

Wafik S. El-Deiry

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Código Libristo: 02644035

Editores Humana Press Inc., octubre 2013

The second volume of Tumor Suppressor Genes explores the cell biology and biochemical function of th... Descripción completa

Código Libristo: 02644035

298 b

121.69 €

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The second volume of Tumor Suppressor Genes explores the cell biology and biochemical function of the tumor suppressor genes, as well as its physiological role in vivo. The authors detail the physical methods (NMR, microarray approaches, pot-translational structure analysis, analysis of regulation at the gene expression and protein signaling levels)used to understand the function of tumor suppressor genes. In vivo approaches discussed include studies in yeast, Drosophilia, mice, and human tumors. §For both volumes:§Leading physician scientists and academic researchers review all the known tumor suppressor genes, explain how they work, and describe how they were discovered and isolated. In many cases, the authors discuss specific genes that are frequently involved in hereditary or sporadic cancers. They also provide a detailed guide to using powerful molecular genetic, cytogenetic, proteomic, and cell biological strategies to discover and isolate novel tumor suppressor genes and their targets. A second volume of this two-volume set, Tumor Suppressor Genes, Volume 2: Regulation, Function, and Medical Applications, shows how to explore the cell biology and biochemical function of such encoded proteins, to study its physiological role in vivo, and to use information on TSGs to develop diagnostic and therapeutic strategies for cancer.